Promoter Polymorphisms in ACE (Angiotensin I–Converting Enzyme) Associated With Clinical Outcomes in Hypertension

Genetic variants of ACE are suspected risk factors in cardiovascular disease, but the alleles responsible for the variations remain unidentified. To search for regulatory polymorphisms, allelic angiotensin I–converting enzyme (ACE) mRNA expression was measured in 65 heart tissues, followed by genoty...

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Autors principals: Johnson, AD, Gong, Y, Wang, D, Langaee, TY, Shin, J, Cooper-DeHoff, RM, Schork, NJ, Binkley, P, Pepine, CJ, Johnson, JA, Sadee, W
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709290/
https://ncbi.nlm.nih.gov/pubmed/18946466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2008.194
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