A Histone H2A Deubiquitinase Complex Coordinating Histone Acetylation and H1 Dissociation in Transcriptional Regulation

Deciphering the epigenetic “code” remains a central issue in transcriptional regulation. Here, we report the identification of a MPN(+)/JAMM domain-containing histone H2A deubiquitinase (2A-DUB, or KIAA1915/MYSM1) specific for monoubiquitinated H2A (uH2A), that has permitted delineation of a strateg...

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Autors principals: Zhu, Ping, Zhou, Wenlai, Wang, Jianxun, Puc, Janusz, Ohgi, Kenneth A., Erdjument-Bromage, Hediye, Tempst, Paul, Glass, Christopher K., Rosenfeld, Michael G.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709280/
https://ncbi.nlm.nih.gov/pubmed/17707232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.07.024
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