Antigen Specificity of Clonally Expanded and Receptor Edited Cerebrospinal Fluid B cells from Patients with Relapsing Remitting MS

We re-engineered the immunoglobulin rearrangements from clonally expanded CSF B cells of three Multiple Sclerosis patients as Fab fragments, and used three methods to test for their Ag-specificity. Nine out of ten Fab fragments were reactive to Myelin Basic Protein (MBP). The one Fab that did not re...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Lambracht-Washington, Doris, O’Connor, Kevin C., Cameron, Elizabeth, Jowdry, Andrea, Ward, E. Sally, Frohman, Elliot, Racke, Michael K., Monson, Nancy L.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709235/
https://ncbi.nlm.nih.gov/pubmed/17451814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.03.002
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items