Mutation analysis of the hyperpolarization-activated cyclic nucleotide-gated channels HCN1 and HCN2 in idiopathic generalized epilepsy

Hyperpolarization-activated cyclic nucleotide-gated (HCN1-4) channels play an important role in the regulation of neuronal rhythmicity. In the present study we describe the mutation analysis of HCN1 and HCN2 in 84 unrelated patients with idiopathic generalized epilepsy (IGE). Several functional vari...

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Bibliografiske detaljer
Main Authors: Tang, Bin, Sander, Thomas, Craven, Kimberley B., Hempelmann, Anne, Escayg, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709210/
https://ncbi.nlm.nih.gov/pubmed/17931874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.08.006
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