MYCN Silencing Induces Differentiation and Apoptosis in Human Neuroblastoma Cells

MYCN amplification strongly correlates with unfavorable outcomes in patients with neuroblastoma. The aim of this study was to investigate the role of MYCN in neuroblastoma cell differentiation and apoptosis. We used the technique of RNA interference to inhibit MYCN gene expression in neuroblastoma c...

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Autori principali: Kang, Junghee, Rychahou, Piotr G., Ishola, Titilope A., Qiao, Jingbo, Evers, B. Mark, Chung, Dai H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708968/
https://ncbi.nlm.nih.gov/pubmed/17055458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.10.020
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