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Anaplastic lymphoma kinase: signalling in development and disease

RTKs (receptor tyrosine kinases) play important roles in cellular proliferation and differentiation. In addition, RTKs reveal oncogenic potential when their kinase activities are constitutively enhanced by point mutation, amplification or rearrangement of the corresponding genes. The ALK (anaplastic...

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Detalhes bibliográficos
Main Authors: Palmer, Ruth H., Vernersson, Emma, Grabbe, Caroline, Hallberg, Bengt
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708929/
https://ncbi.nlm.nih.gov/pubmed/19459784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090387
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