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Dysregulation of Human β-Defensin-2 Protein in Inflammatory Bowel Disease
BACKGROUND: Human β-defensin-2 (HBD2) is an antimicrobial peptide implicated in the pathogenesis of inflammatory bowel disease (IBD). Low copy number and concomitant low mRNA expression of the HBD2 gene have been implicated in susceptibility to colonic Crohn's Disease (CD). We investigated the...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708916/ https://ncbi.nlm.nih.gov/pubmed/19617917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006285 |
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