7-Ketocholesterol Incorporation into Sphingolipid/Cholesterol-enriched (Lipid Raft) Domains Is Impaired by Vitamin E: A SPECIFIC ROLE FOR α-TOCOPHEROL WITH CONSEQUENCES ON CELL DEATH

Cholesterol oxides, in particular 7-ketocholesterol, are proatherogenic compounds that induce cell death in the vascular wall when localized in lipid raft domains of the cell membrane. Deleterious effects of 7-ketocholesterol can be prevented by vitamin E, but the molecular mechanism involved is unc...

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Detalhes bibliográficos
Principais autores: Royer, Marie-Charlotte, Lemaire-Ewing, Stéphanie, Desrumaux, Catherine, Monier, Serge, Pais de Barros, Jean-Paul, Athias, Anne, Néel, Dominique, Lagrost, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708879/
https://ncbi.nlm.nih.gov/pubmed/19351882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808641200
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