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Structural Basis for Antibody Discrimination between Two Hormones That Recognize the Parathyroid Hormone Receptor

Parathyroid hormone-related protein (PTHrP) plays a vital role in the embryonic development of the skeleton and other tissues. When it is produced in excess by cancers it can cause hypercalcemia, and its local production by breast cancer cells has been implicated in the pathogenesis of bone metastas...

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Autores principales: McKinstry, William J., Polekhina, Galina, Diefenbach-Jagger, Hannelore, Ho, Patricia W. M., Sato, Koh, Onuma, Etsuro, Gillespie, Matthew T., Martin, T. John, Parker, Michael W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708852/
https://ncbi.nlm.nih.gov/pubmed/19346515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900044200
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