Degradation of ppGpp by Nudix Pyrophosphatase Modulates the Transition of Growth Phase in the Bacterium Thermus thermophilus

A major bacterial alarmone, guanosine 3′,5′-bispyrophosphate (ppGpp), controls cellular growth under conditions of nutritional starvation. For most bacteria, intracellular ppGpp levels are tightly controlled by the synthesis/degradation cycle of RelA and SpoT activities. This study shows a novel ppG...

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Bibliografske podrobnosti
Main Authors: Ooga, Takushi, Ohashi, Yoshiaki, Kuramitsu, Seiki, Koyama, Yoshinori, Tomita, Masaru, Soga, Tomoyoshi, Masui, Ryoji
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Enzyme Catalysis and Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708851/
https://ncbi.nlm.nih.gov/pubmed/19346251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900582200
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