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Structural Basis for Different Substrate Specificities of Two ADP-Ribose Pyrophosphatases from Thermus thermophilus HB8

ADP-ribose (ADPR) is one of the main substrates of Nudix proteins. Among the eight Nudix proteins of Thermus thermophilus HB8, we previously determined the crystal structure of Ndx4, an ADPR pyrophosphatase (ADPRase). In this study we show that Ndx2 of T. thermophilus also preferentially hydrolyzes...

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Bibliografiske detaljer
Main Authors: Wakamatsu, Taisuke, Nakagawa, Noriko, Kuramitsu, Seiki, Masui, Ryoji
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223557/
https://ncbi.nlm.nih.gov/pubmed/18039767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01522-07
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