High Fat Diet Induced Hepatic Steatosis Establishes a Permissive Microenvironment for Colorectal Metastases and Promotes Primary Dysplasia in a Murine Model

Non-alcoholic fatty liver disease (NAFLD), which includes steatosis and its progression to non-alcoholic steatohepatitis, is a liver disorder of increasing clinical significance. Here we characterize a murine model of high fat diet-induced NAFLD with progression from liver steatosis to histological...

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Detalhes bibliográficos
Main Authors: VanSaun, Michael Nathan, Lee, In Kyu, Washington, Mary Kay, Matrisian, Lynn, Gorden, David Lee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708821/
https://ncbi.nlm.nih.gov/pubmed/19541928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080703
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