Deregulation of IKBKE Is Associated with Tumor Progression, Poor Prognosis, and Cisplatin Resistance in Ovarian Cancer

I-kappa-B kinase e (IKBKE; IKKε) has been recently identified as a breast cancer oncogene, and its alteration appears to be an early event in breast cancer development. In this study, we demonstrated that IKKε is frequently overexpressed and activated in human ovarian cancer cell lines and primary t...

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Hauptverfasser: Guo, Jian-Ping, Shu, Shao-Kun, He, Lili, Lee, Yi-Chun, Kruk, Patricia A., Grenman, Seija, Nicosia, Santo V., Mor, Gil, Schell, Michael J., Coppola, Domenico, Cheng, Jin Q.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708818/
https://ncbi.nlm.nih.gov/pubmed/19497997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080767
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