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Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency

Asparagine-linked glycosylation is a common posttranslational modification of diverse secretory and membrane proteins in eukaryotes, where it is catalyzed by the multiprotein complex oligosaccharyltransferase. The functions of the protein subunits of oligoasccharyltransferase, apart from the catalyt...

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Détails bibliographiques
Auteurs principaux: Schulz, Benjamin L., Stirnimann, Christian U., Grimshaw, John P. A., Brozzo, Maurice S., Fritsch, Fabienne, Mohorko, Elisabeth, Capitani, Guido, Glockshuber, Rudi, Grütter, Markus G., Aebi, Markus
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708779/
https://ncbi.nlm.nih.gov/pubmed/19549845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812515106
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