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Analysis of substrate specificity of Trypanosoma brucei oligosaccharyltransferases (OSTs) by functional expression of domain-swapped chimeras in yeast

N-Linked protein glycosylation is an essential and highly conserved post-translational modification in eukaryotes. The transfer of a glycan from a lipid-linked oligosaccharide (LLO) donor to the asparagine residue of a nascent polypeptide chain is catalyzed by an oligosaccharyltransferase (OST) in t...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Poljak, Kristina, Breitling, Jörg, Gauss, Robert, Rugarabamu, George, Pellanda, Mauro, Aebi, Markus
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724018/
https://ncbi.nlm.nih.gov/pubmed/29042445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.811133
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