Essential role of the Ly49A stalk region for immunological synapse formation and signaling

NK cells use surface NK receptors to discriminate self from non-self. The NK receptor ligand-binding domain (NKD) has been considered the sole regulator of ligand binding. Using a prototypic murine NK receptor, Ly49A, we show that the membrane proximal nonligand binding ecto-domain (the stalk region...

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Detaylı Bibliyografya
Asıl Yazarlar: Ito, Daisuke, Iizuka, Yoshie-Matsubayashi, Katepalli, Madhu P., Iizuka, Koho
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708761/
https://ncbi.nlm.nih.gov/pubmed/19549850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900664106
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