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Impairment of Immunological Synapse Formation in Adaptively Tolerant T cells

Adaptive tolerance is a hyporesponsive state in which lymphocyte antigen receptor signaling becomes desensitized following prolonged in vivo encounter with antigen. The molecular mechanisms underlying this hyporesponsive state in T cells are not fully understood, although a major signaling block has...

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Detalhes bibliográficos
Main Authors: Choi, Seeyoung, Schwartz, Ronald H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131438/
https://ncbi.nlm.nih.gov/pubmed/21685322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003314
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