Crystal structure of type I ryanodine receptor amino-terminal β-trefoil domain reveals a disease-associated mutation “hot spot” loop

Muscle contraction and relaxation is regulated by transient elevations of myoplasmic Ca(2+). Ca(2+) is released from stores in the lumen of the sarco(endo)plasmic reticulum (SER) to initiate formation of the Ca(2+) transient by activation of a class of Ca(2+) release channels referred to as ryanodin...

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Detaylı Bibliyografya
Asıl Yazarlar: Amador, Fernando J., Liu, Shuang, Ishiyama, Noboru, Plevin, Michael J., Wilson, Aaron, MacLennan, David H., Ikura, Mitsuhiko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708722/
https://ncbi.nlm.nih.gov/pubmed/19541610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905186106
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