A mechanosensitive transcriptional mechanism that controls angiogenesis

Angiogenesis is controlled by physical interactions between cells and extracellular matrix as well as soluble angiogenic factors, such as VEGF. However, the mechanism by which mechanical signals integrate with other microenvironmental cues to regulate neovascularization remains unknown. Here we show...

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Main Authors: Mammoto, Akiko, Connor, Kip M., Mammoto, Tadanori, Yung, Chong Wing, Huh, Dongeun, Aderman, Christopher M., Mostoslavsky, Gustavo, Smith, Lois E. H., Ingber, Donald E.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708674/
https://ncbi.nlm.nih.gov/pubmed/19242469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07765
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