Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation

Mesenchymal condensation is critical for organogenesis, yet little is known about how this process is controlled. Here we show that Fgf8 and Sema3f produced by early dental epithelium respectively attract and repulse mesenchymal cells, which causes them to pack tightly together during mouse tooth de...

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Main Authors: Mammoto, Tadanori, Mammoto, Akiko, Torisawa, Yu-suke, Tat, Tracy, Gibbs, Ashley, Derda, Ratmir, Mannix, Robert, de Bruijn, Marlieke, Yung, Chong Wing, Huh, Dongeun, Ingber, Donald E.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199351/
https://ncbi.nlm.nih.gov/pubmed/21924961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.07.006
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