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Complete Virion Assembly with Scaffolding Proteins Altered in the Ability To Perform a Critical Conformational Switch

In the φX174 procapsid, 240 external scaffolding proteins form a nonquasiequivalent lattice. To achieve this arrangement, the four structurally unique subunits must undergo position-dependent conformational switches. One switch is mediated by glycine residue 61, which allows a 30° kink to form in α-...

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Detalhes bibliográficos
Main Authors: Cherwa, James E., Fane, Bentley A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708623/
https://ncbi.nlm.nih.gov/pubmed/19474099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00479-09
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