Listeria monocytogenes 6-Phosphogluconolactonase Mutants Induce Increased Activation of a Host Cytosolic Surveillance Pathway

Infection with wild-type Listeria monocytogenes activates a host cytosolic surveillance response characterized by the expression of beta interferon (IFN-β). We performed a genetic screen to identify L. monocytogenes transposon insertion mutants that induced altered levels of host IFN-β expression. O...

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Main Authors: Crimmins, Gregory T., Schelle, Michael W., Herskovits, Anat A., Ni, Peggy P., Kline, Benjamin C., Meyer-Morse, Nicole, Iavarone, Anthony T., Portnoy, Daniel A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708561/
https://ncbi.nlm.nih.gov/pubmed/19398547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01511-08
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