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Mutations of the Listeria monocytogenes Peptidoglycan N-Deacetylase and O-Acetylase Result in Enhanced Lysozyme Sensitivity, Bacteriolysis, and Hyperinduction of Innate Immune Pathways

Listeria monocytogenes is a Gram-positive intracellular pathogen that is naturally resistant to lysozyme. Recently, it was shown that peptidoglycan modification by N-deacetylation or O-acetylation confers resistance to lysozyme in various Gram-positive bacteria, including L. monocytogenes. L. monocy...

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Autors principals: Rae, Chris S., Geissler, Aimee, Adamson, Paul C., Portnoy, Daniel A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165460/
https://ncbi.nlm.nih.gov/pubmed/21768286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00077-11
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