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CspA-Mediated Binding of Human Factor H Inhibits Complement Deposition and Confers Serum Resistance in Borrelia burgdorferi

Borrelia burgdorferi has developed efficient mechanisms for evading the innate immune response during mammalian infection and has been shown to be resistant to the complement-mediated bactericidal activity of human serum. It is well recognized that B. burgdorferi expresses multiple lipoproteins on i...

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Detalhes bibliográficos
Main Authors: Kenedy, Melisha R., Vuppala, Santosh R., Siegel, Corinna, Kraiczy, Peter, Akins, Darrin R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708555/
https://ncbi.nlm.nih.gov/pubmed/19451251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00318-09
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