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CspA-Mediated Binding of Human Factor H Inhibits Complement Deposition and Confers Serum Resistance in Borrelia burgdorferi

Borrelia burgdorferi has developed efficient mechanisms for evading the innate immune response during mammalian infection and has been shown to be resistant to the complement-mediated bactericidal activity of human serum. It is well recognized that B. burgdorferi expresses multiple lipoproteins on i...

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Bibliografiske detaljer
Main Authors: Kenedy, Melisha R., Vuppala, Santosh R., Siegel, Corinna, Kraiczy, Peter, Akins, Darrin R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708555/
https://ncbi.nlm.nih.gov/pubmed/19451251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00318-09
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