Role of Teichoic Acid Choline Moieties in the Virulence of Streptococcus pneumoniae

In recent reports it was shown that genetically modified choline-free strains of Streptococcus pneumoniae (D39Cho(−)licA64 and D39ChiplicB31) expressing the type II capsular polysaccharide were virtually avirulent in the murine sepsis model, in sharp contrast to the isogenic and highly virulent stra...

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Bibliographische Detailangaben
Hauptverfasser: Gehre, Florian, Spisek, Radek, Kharat, Arun S., Matthews, Phillip, Kukreja, Anjli, Anthony, Robert M., Dhodapkar, Madhav V., Vollmer, Waldemar, Tomasz, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Molecular Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708541/
https://ncbi.nlm.nih.gov/pubmed/19433549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00986-08
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