Peptidoglycan N-Acetylglucosamine Deacetylase, a Putative Virulence Factor in Streptococcus pneumoniae

Many glucosamine residues of the pneumococcal peptidoglycan (PG) are not acetylated, which makes the PG resistant to lysozyme. A capsular type III mutant with an inactivated pgdA gene (encoding the peptidoglycan N-acetylglucosamine deacetylase A) became hypersensitive to exogenous lysozyme and showe...

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Bibliographic Details
Main Authors: Vollmer, Waldemar, Tomasz, Alexander
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC133073/
https://ncbi.nlm.nih.gov/pubmed/12438406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.7176-7178.2002
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