Inactivation of contraceptive steroid hormones by human intestinal clostridia.
Steroid hormones reduced in ring-A are devoid of hormonal activity. In metabolic experiments we found that human fecal flora reduced the delta 4-3-keto structure of natural progestins to 3 alpha-hydroxy, 5 beta-steroid metabolites (3 alpha,5 beta) and of synthetic progestins to a mixture of 3 alpha,...
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| Published in: | J Clin Microbiol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1983
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC270842/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6630441/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.18.3.500-504.1983 |
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