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Inactivation of contraceptive steroid hormones by human intestinal clostridia.

Steroid hormones reduced in ring-A are devoid of hormonal activity. In metabolic experiments we found that human fecal flora reduced the delta 4-3-keto structure of natural progestins to 3 alpha-hydroxy, 5 beta-steroid metabolites (3 alpha,5 beta) and of synthetic progestins to a mixture of 3 alpha,...

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Bibliografski detalji
Glavni autori: Bokkenheuser, V D, Winter, J, Cohen, B I, O'Rourke, S, Mosbach, E H
Format: Artigo
Jezik:Inglês
Izdano: 1983
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC270842/
https://ncbi.nlm.nih.gov/pubmed/6630441
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