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Inactivation of contraceptive steroid hormones by human intestinal clostridia.
Steroid hormones reduced in ring-A are devoid of hormonal activity. In metabolic experiments we found that human fecal flora reduced the delta 4-3-keto structure of natural progestins to 3 alpha-hydroxy, 5 beta-steroid metabolites (3 alpha,5 beta) and of synthetic progestins to a mixture of 3 alpha,...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
1983
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC270842/ https://ncbi.nlm.nih.gov/pubmed/6630441 |
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