Effect of biliary obstruction and internal biliary drainage on hepatic cytochrome P450 isozymes in rats

AIM: To investigate the total cytochrome P450 (CYP) content, microsomal mixed-function oxidase (MFO) activity, and expression of mRNAs for various CYP isozymes in a simple rat model of reversible obstructive jaundice. METHODS: Obstructive jaundice was created in male rats by causing bile duct obstru...

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Bibliographic Details
Main Authors: Fukushima, Shintaro, Okuno, Hiroyasu, Shibatani, Nobuyuki, Nakahashi, Yoshitsugu, Seki, Toshihito, Okazaki, Kazuichi
Format: Artigo
Language:Inglês
Published: The WJG Press and Baishideng 2008
Subjects:
Rapid Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708369/
https://ncbi.nlm.nih.gov/pubmed/18442205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.2556
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