Oral vaccination with a recombinant Salmonella vaccine vector provokes systemic HIV-1 subtype C Gag-specific CD4+ Th1 and Th2 cell immune responses in mice

BACKGROUND: Recombinant Salmonella vaccine vectors may potentially be used to induce specific CD4+ T cell responses against foreign viral antigens. Such immune responses are required features of vaccines against pathogens such as human immunodeficiency virus type 1 (HIV-1). The aim of this study was...

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Bibliographic Details
Main Authors: Chin'ombe, Nyasha, Bourn, William R, Williamson, Anna-Lise, Shephard, Enid G
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708135/
https://ncbi.nlm.nih.gov/pubmed/19555490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-87
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