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Overexpression of recombinant HIV-1 Subtype C Tat and Nef in a Salmonella vaccine vector

Tat and Nef are very important regulatory proteins of HIV-1. They enhance viral replication and down-regulate expression of MHC Class I molecules, respectively. The antigens are now considered to be targets for HIV vaccine development. The expression of Tat and Nef in Salmonella vaccines has not pre...

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Hlavní autoři: Chin’ombe, Nyasha, Lebeko, Maribanyana, Kgatle, Mankgopo
Médium: Artigo
Jazyk:Inglês
Vydáno: The African Field Epidemiology Network 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909692/
https://ncbi.nlm.nih.gov/pubmed/24498468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11604/pamj.2013.16.19.2759
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