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T-817MA, a neurotrophic agent, ameliorates the deficits in adult neurogenesis and spatial memory in rats infused i.c.v. with amyloid-β peptide

BACKGROUND AND PURPOSE: Adult neurogenesis occurs throughout life in the subgranular zone and the dentate gyrus of the hippocampus. Deficient neurogenesis may be responsible for deficient hippocampal functions in neurodegenerative disorders such as Alzheimer's disease (AD). T-817MA [1-{3-[2-(1-...

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Autori principali: Kimura, Tatsuo, Nguyen, Phuong Thi Hong, Ho, Son Anh, Tran, Anh Hai, Ono, Taketoshi, Nishijo, Hisao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707991/
https://ncbi.nlm.nih.gov/pubmed/19371351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00141.x
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