T-817MA, a neurotrophic agent, ameliorates the deficits in adult neurogenesis and spatial memory in rats infused i.c.v. with amyloid-β peptide

BACKGROUND AND PURPOSE: Adult neurogenesis occurs throughout life in the subgranular zone and the dentate gyrus of the hippocampus. Deficient neurogenesis may be responsible for deficient hippocampal functions in neurodegenerative disorders such as Alzheimer's disease (AD). T-817MA [1-{3-[2-(1-...

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Main Authors: Kimura, Tatsuo, Nguyen, Phuong Thi Hong, Ho, Son Anh, Tran, Anh Hai, Ono, Taketoshi, Nishijo, Hisao
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2009
主題:
Research Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707991/
https://ncbi.nlm.nih.gov/pubmed/19371351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00141.x
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