Effects of zotepine on extracellular levels of monoamine, GABA and glutamate in rat prefrontal cortex

BACKGROUND AND PURPOSE: The atypical antipsychotic drug, zotepine, is effective in treatment of schizophrenia and acute mania, but the incidence of seizures during treatment is higher than with other antipsychotics. In addition, the mechanisms underlying the clinical actions of zotepine remain uncha...

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Bibliographic Details
Main Authors: Yamamura, S, Ohoyama, K, Hamaguchi, T, Nakagawa, M, Suzuki, D, Matsumoto, T, Motomura, E, Tanii, H, Shiroyama, T, Okada, M
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2009
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707977/
https://ncbi.nlm.nih.gov/pubmed/19371334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00175.x
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