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Repeated phencyclidine administration alters glutamate release and decreases GABA markers in the prefrontal cortex of rats
Repeated phencyclidine (PCP) administration induces cognitive disruptions resembling those seen in schizophrenia. Alterations in glutamate transmission and γ-aminobutyric acid (GABA) function in the prefrontal cortex (PFC) have been implicated in these PCP-induced deficits, as well as in cognitive s...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107933/ https://ncbi.nlm.nih.gov/pubmed/21238466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.01.008 |
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