Increased endothelin-1 reactivity and endothelial dysfunction in carotid arteries from rats with hyperhomocysteinemia

BACKGROUND AND PURPOSE: There are interactions between endothelin-1 (ET-1) and endothelial vascular injury in hyperhomocysteinemia (HHcy), but the underlying mechanisms are poorly understood. Here we evaluated the effects of HHcy on the endothelin system in rat carotid arteries. EXPERIMENTAL APPROAC...

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Autori principali: de Andrade, CR, Leite, PF, Montezano, AC, Casolari, DA, Yogi, A, Tostes, RC, Haddad, R, Eberlin, MN, Laurindo, FRM, de Souza, HP, Corrêa, FMA, de Oliveira, AM
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2009
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Themed Section: Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707970/
https://ncbi.nlm.nih.gov/pubmed/19371338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00165.x
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