Increased endothelin-1 reactivity and endothelial dysfunction in carotid arteries from rats with hyperhomocysteinemia

BACKGROUND AND PURPOSE: There are interactions between endothelin-1 (ET-1) and endothelial vascular injury in hyperhomocysteinemia (HHcy), but the underlying mechanisms are poorly understood. Here we evaluated the effects of HHcy on the endothelin system in rat carotid arteries. EXPERIMENTAL APPROAC...

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Detalhes bibliográficos
Main Authors: de Andrade, CR, Leite, PF, Montezano, AC, Casolari, DA, Yogi, A, Tostes, RC, Haddad, R, Eberlin, MN, Laurindo, FRM, de Souza, HP, Corrêa, FMA, de Oliveira, AM
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Themed Section: Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707970/
https://ncbi.nlm.nih.gov/pubmed/19371338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00165.x
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