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Evaluation of PDE4 inhibition for COPD

Targeting type 4 phosphodiesterase (PDE4) for treatment of COPD has multilevel benefits to patients by reducing inflammation, relieving bronchoconstriction, and improving pulmonary circulation. The isoenzyme-specific narrow spectrum PDE4 inhibitors such as cilomilast and roflumilast may have limited...

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Detalhes bibliográficos
Main Authors: Wang, Desuo, Cui, Xiangli
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707810/
https://ncbi.nlm.nih.gov/pubmed/18044094
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