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Varenicline has antidepressant-like activity in the forced swim test and augments sertraline’s effect

Varenicline, an α4β2 nicotinic acetylcholine receptor partial agonist developed as a smoking cessation aid, showed antidepressant-like activity in the forced swim test in two mouse strains. In addition, a low varenicline dose significantly enhanced the effects of moderately active doses of the selec...

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Detalhes bibliográficos
Main Authors: Rollema, Hans, Guanowsky, Victor, Mineur, Yann S., Shrikhande, Alka, Coe, Jotham W., Seymour, Patricia A., Picciotto, Marina R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707785/
https://ncbi.nlm.nih.gov/pubmed/19168054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2009.01.002
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