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Protease Activated Receptor Signaling Is Required for African Trypanosome Traversal of Human Brain Microvascular Endothelial Cells

BACKGROUND: Using human brain microvascular endothelial cells (HBMECs) as an in vitro model for how African trypanosomes cross the human blood-brain barrier (BBB) we recently reported that the parasites cross the BBB by generating calcium activation signals in HBMECs through the activity of parasite...

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書誌詳細
主要な著者: Grab, Dennis J., Garcia-Garcia, Jose C., Nikolskaia, Olga V., Kim, Yuri V., Brown, Amanda, Pardo, Carlos A., Zhang, Yongqing, Becker, Kevin G., Wilson, Brenda A., de A. Lima, Ana Paula C., Scharfstein, Julio, Dumler, J. Stephen
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707606/
https://ncbi.nlm.nih.gov/pubmed/19621073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000479
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