Protease Activated Receptor Signaling Is Required for African Trypanosome Traversal of Human Brain Microvascular Endothelial Cells

BACKGROUND: Using human brain microvascular endothelial cells (HBMECs) as an in vitro model for how African trypanosomes cross the human blood-brain barrier (BBB) we recently reported that the parasites cross the BBB by generating calcium activation signals in HBMECs through the activity of parasite...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Grab, Dennis J., Garcia-Garcia, Jose C., Nikolskaia, Olga V., Kim, Yuri V., Brown, Amanda, Pardo, Carlos A., Zhang, Yongqing, Becker, Kevin G., Wilson, Brenda A., de A. Lima, Ana Paula C., Scharfstein, Julio, Dumler, J. Stephen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707606/
https://ncbi.nlm.nih.gov/pubmed/19621073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000479
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