Coordinate Control of Expression of Nrf2-Modulated Genes in the Human Small Airway Epithelium Is Highly Responsive to Cigarette Smoking

Nuclear factor erythroid 2–related factor 2 (Nrf2) is an oxidant-responsive transcription factor known to induce detoxifying and antioxidant genes. Cigarette smoke, with its large oxidant content, is a major stress on the cells of small airway epithelium, which are vulnerable to oxidant damage. We a...

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Detalhes bibliográficos
Main Authors: Hübner, Ralf-Harto, Schwartz, Jamie D, De Bishnu, P, Ferris, Barbara, Omberg, Larsson, Mezey, Jason G, Hackett, Neil R, Crystal, Ronald G
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707520/
https://ncbi.nlm.nih.gov/pubmed/19593404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2008.00130
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