Biologic Phenotyping of the Human Small Airway Epithelial Response to Cigarette Smoking

BACKGROUND: The first changes associated with smoking are in the small airway epithelium (SAE). Given that smoking alters SAE gene expression, but only a fraction of smokers develop chronic obstructive pulmonary disease (COPD), we hypothesized that assessment of SAE genome-wide gene expression would...

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Detalhes bibliográficos
Main Authors: Tilley, Ann E., O'Connor, Timothy P., Hackett, Neil R., Strulovici-Barel, Yael, Salit, Jacqueline, Amoroso, Nancy, Zhou, Xi Kathy, Raman, Tina, Omberg, Larsson, Clark, Andrew, Mezey, Jason, Crystal, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145669/
https://ncbi.nlm.nih.gov/pubmed/21829517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022798
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