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Nutritional regulation of the fatty acid synthase promoter in vivo: Sterol regulatory element binding protein functions through an upstream region containing a sterol regulatory element

The transcription of fatty acid synthase (FAS), a central enzyme in de novo lipogenesis, is dramatically induced by fasting/refeeding and insulin. We reported that upstream stimulatory factor binding to the −65 E-box is required for induction of the FAS transcription by insulin in 3T3-L1 adipocytes....

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Главные авторы: Latasa, Maria-Jesus, Moon, Yang Soo, Kim, Kee-Hong, Sul, Hei Sook
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2000
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC27074/
https://ncbi.nlm.nih.gov/pubmed/10962028
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