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Insulin induction of glucokinase and fatty acid synthase in hepatocytes: analysis of the roles of sterol-regulatory-element-binding protein-1c and liver X receptor

The transcription activator SREBP-1c (sterol-regulatory-element-binding protein-1c) is induced by insulin in the liver and is considered a master regulator of lipogenic genes such as FASN (fatty acid synthase). The question of whether SREBP-1c is also a mediator of insulin action on the regulatory e...

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Detalhes bibliográficos
Main Authors: Hansmannel, Franck, Mordier, Sylvie, Iynedjian, Patrick B.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1609914/
https://ncbi.nlm.nih.gov/pubmed/16834571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060811
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