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Truncation in the tcdC region of the Clostridium difficile PathLoc of clinical isolates does not predict increased biological activity of Toxin B or Toxin A

BACKGROUND: The increased severity of disease associated with the NAP1 strain of Clostridium difficile has been attributed to mutations to the tcdC gene which codes for a negative regulator of toxin production. To assess the role of hyper-production of Toxins A and B in clinical isolates of Clostrid...

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Detalhes bibliográficos
Main Authors: Murray, Ruth, Boyd, Dave, Levett, Paul N, Mulvey, Michael R, Alfa, Michelle J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707377/
https://ncbi.nlm.nih.gov/pubmed/19558711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-9-103
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