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Vault Nanoparticles Containing an Adenovirus-Derived Membrane Lytic Protein Facilitate Toxin and Gene Transfer

Non-viral methods of gene delivery possess several advantages over that of viral-based vectors including having increased safety. However, the ability to achieve effective transport of therapeutic molecules across host cell membranes via non-viral methods remains a significant goal. Cell-derived nan...

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Detalhes bibliográficos
Main Authors: Lai, Cheng-Yu, Wiethoff, Chris M., Kickhoefer, Valerie A., Rome, Leonard H., Nemerow, Glen R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707358/
https://ncbi.nlm.nih.gov/pubmed/19226129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn8008504
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