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An ab Initio Structural Model of a Nucleoside Permease Predicts Functionally Important Residues

Permeases belonging to the equilibrative nucleoside transporter family promote uptake of nucleosides and/or nucleobases into a wide range of eukaryotes and mediate the uptake of a variety of drugs used in the treatment of cancer, heart disease, AIDS, and parasitic infections. No experimental three-d...

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Библиографические подробности
Главные авторы: Valdés, Raquel, Arastu-Kapur, Shirin, Landfear, Scott M., Shinde, Ujwal
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707223/
https://ncbi.nlm.nih.gov/pubmed/19429678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017947
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