Загрузка...

Caspase-cleaved Tau Expression Induces Mitochondrial Dysfunction in Immortalized Cortical Neurons: IMPLICATIONS FOR THE PATHOGENESIS OF ALZHEIMER DISEASE

In Alzheimer disease (AD) mitochondrial abnormalities occur early in the pathogenic process and likely play a significant role in disease progression. Tau is a microtubule-associated protein that is abnormally processed in AD, and a connection between tau pathology and mitochondrial impairment has b...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Quintanilla, Rodrigo A., Matthews-Roberson, Tori A., Dolan, Philip J., Johnson, Gail V. W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707209/
https://ncbi.nlm.nih.gov/pubmed/19389700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808908200
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!