Sgt1 Dimerization Is Negatively Regulated by Protein Kinase CK2-mediated Phosphorylation at Ser(361)

The kinetochore, which consists of centromere DNA and structural proteins, is essential for proper chromosome segregation in eukaryotes. In budding yeast, Sgt1 and Hsp90 are required for the binding of Skp1 to Ctf13 (a component of the core kinetochore complex CBF3) and therefore for the assembly of...

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Bibliographic Details
Main Authors: Bansal, Parmil K., Mishra, Ashutosh, High, Anthony A., Abdulle, Rashid, Kitagawa, Katsumi
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707205/
https://ncbi.nlm.nih.gov/pubmed/19398558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.012732
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